Volume: 71s1 - Number: - year 2000



Summary   





OPEN SESSION Chairperson: Professor Baohong Ji

Objectives of the meeting
Baohong Ji
DOI: 10.5935/0305-7518.20000058

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Leprosy research and elimination
S. K. Noordeen
DOI: 10.5935/0305-7518.20000059

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SESSSION II: PROPHYLAXIS
Chairperson: Dr S. K. Noordeen

Prophylaxis-scope and limitations
S. K. Noordeen
DOI: 10.5935/0305-7518.20000060

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Leprosy chemoprophylaxis in Micronesia
C. Diletto and L. Blanc
DOI: 10.5935/0305-7518.20000061

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Approaches to studying the transmission of Mycobacterium leprae
MILEP2 Study Group
DOI: 10.5935/0305-7518.20000062

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Strategies for pro-active case-finding in leprosy control
P. R. Klatser
DOI: 10.5935/0305-7518.20000063

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Chemoprophylaxis of leprosy in the Southern Marquesas with a single 25 mg/kg dose of rifampicin. Results after 10 years
L. N. Nguyen, J. L. Cartel and J. H. Grosset
DOI: 10.5935/0305-7518.20000064

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Chemoprophylaxis against leprosy: expectations and methodology of a trial
P. Vijayakumaran, P. Krishnamurthy, P. Rao and E. Declerq
DOI: 10.5935/0305-7518.20000065

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SESSION III: IMMUNODIAGNOSIS
Chairperson: Professor Patrick Brennan

South India immunoprophylaxis trial against leprosy: relevance of the findings in the context of trends in leprosy
M. D. Gupte
DOI: 10.5935/0305-7518.20000066

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Skin test development in leprosy: progress with first-generation skin test antigens, and an approach to the second generation
P. J. Brennan
DOI: 10.5935/0305-7518.20000067

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Diagnostic assays for leprosy based on T-cell epitopes
H. M. Dockrell, S. Brahmbhatt, B. D. Robertson, S. Britton, U. Fruth, N. Gebre, M. Hunegnaw, R. Hussan, R. Manadhar, l. Murrillo, M. C. V. Pessolani, P. Roche, J. L. Salgado, E. Sampaio, F. Shahid, J. E. R. Thole and D. B. Young
DOI: 10.5935/0305-7518.20000068

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Whole blood assays for interferon-γ: practicalities and potential for use as diagnostic tests in the field
H. M. Dockrell, G. F. Black, R. E. Weir and P. E. M. Fine
DOI: 10.5935/0305-7518.20000069

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Experience and lessons from the use of lepromin and Mycobacterium leprae-specific serology
U. Sengupta
DOI: 10.5935/0305-7518.20000070

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Use of a Mycobacterium leprae dipstick to classify patients with leprosy
P. R. Klatser
DOI: 10.5935/0305-7518.20000071

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SESION IV: CHEMETHERAPY
Chairperson: Professor Jacques Grossep

A rapid, microplate-based assay for evaluating the activity of drugs against Mycobacterium leprae, employing the reduction of Alamar Blue
S. Franzblau
DOI: 10.5935/0305-7518.20000072

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Field trials of a single dose of the combination rifampicin-ofloxacin-minocycline (ROM) for the treatment of paucibacillary leprosy
M. D. Gupte
DOI: 10.5935/0305-7518.20000073

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Combination of rifapentine-moxifloxacin-minocycline (PMM) for the treatment of leprosy
B. Ji and J. Grosset
DOI: 10.5935/0305-7518.20000074

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Current World Health Organization-sponsored studies in the chemotherapy of leprosy
D. Daumerie
DOI: 10.5935/0305-7518.20000075

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Dapsone resistance in Mycobacterium leprae
T. P. Gillis and D. L. Williams
DOI: 10.5935/0305-7518.20000076

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Rapid detection of resistance to rifampicin in Mycobacterium leprae
P. W. Roche, N. Shrestha, A. Thomas, N. Honore and S. T. Cole
DOI: 10.5935/0305-7518.20000077

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The new challenges for chemotherapy research
J. Grosset
DOI: 10.5935/0305-7518.20000078

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SESSION V: REACTIONS AND NERVE DAMAGE
Chairperson: Professor W. Cairns S. Smith

The epidemiology of reactions and nerve damage
P. Saunderson
DOI: 10.5935/0305-7518.20000079

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Steroids in leprosy type 1 (reversal) reactions: mechanisms of action and effectiveness
D. N. J. Lockwood
DOI: 10.5935/0305-7518.20000080

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Role of granulysin in immunity to leprosy
M. T. Ochoa, S. Thoma-Uszynski, P. A. Sieling, S. Sabet, S. Cho, A. M. Krensky, A. Burdik, T. H. Rea and R. L. Modlin
DOI: 10.5935/0305-7518.20000081

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Potential of thalidomide and thalidomide analogues as immunomodulatory drugs in leprosy and leprosy reactions
G. Kaplan
DOI: 10.5935/0305-7518.20000082

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The role of Schwann cells, T cells and Mycobacterium leprae in the immunopathogenesis of nerve damage in leprosy
E. Spierings, T. de Boer, L. Zulianello, T. H. M. Ottenhoff
DOI: 10.5935/0305-7518.20000083

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Dysregulation of IL-4 expression in lepromatous leprosy patients with and without erythema nodosum leprosum
I. Nath, N. Vemuri, A. L. Reddi, M. Bharadwaj, P. Brooks, M. J. Colston, R. S. Misra and V. Ramesh
DOI: 10.5935/0305-7518.20000084

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Review of current research in the prevention of nerve damage in leprosy
W. C. S. Smith
DOI: 10.5935/0305-7518.20000085

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Peripheral neuropathy in leprosy and its consequences
W. H. Van Brakel
DOI: 10.5935/0305-7518.20000086

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Pathogenesis of nerve damage in leprosy: genetic polymorphism regulates the production of TNFα
E. N. Sarno, A. R. Santos, M. R. Jardim, P. N. Suffys, A. S. Almeida, J. A. C. Nery, l. M. M. Vieira and E. P. Sampaio
DOI: 10.5935/0305-7518.20000087

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SESSION VI: BASIC RESEARCH AN PATHONOGENESIS
Chairperson: Dr M. J. Colston

Preliminary analysis of the genome sequence of Mycobacterium leprae
S. T. Cole, N. Honore and K. Eiglmeier
DOI: 10.5935/0305-7518.20000088

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Molecular basis of the interaction of Mycobacterium leprae with peripheral nerve: implications for therapeutic strategies
A. Rambukkana
DOI: 10.5935/0305-7518.20000089

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Exploitation of gene knockout mice models to study the pathogenesis of leprosy
J. Krahenbuhl and L. B. Adams
DOI: 10.5935/0305-7518.20000090

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Immunoprophylaxis against Mycobacterium leprae infection with subunit vaccines
W. J. Britton, E. Martin, A. T. Kamath, K. D. Neupane and P. W. Roche
DOI: 10.5935/0305-7518.20000091

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SESSION VII: PROMOTION OF LEPROSY RESEARCH
Chairperson: Professor Baohong Ji

Leprosy research-setting priorities and facilitating collaborations: a personal perspective
A. M. Ginsberg
DOI: 10.5935/0305-7518.20000092

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Research component in the global alliance
B. Ji
DOI: 10.5935/0305-7518.20000093

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CLOSING SESSION: RECOMMENDATIONS
Chairperson: Professor Baohong Ji

Recommendations
Jacques H. Grosset
DOI: 10.5935/0305-7518.20000094

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